Sweetener in the clear once more


soft drinks

Aspartame is used in many different foods and drinks © Shutterstock

The artificial sweetener aspartame has been given the all-clear by the European Food Safety Authority (EFSA). After an evaluation of ‘all available information’ the authority concluded that aspartame poses no safety concerns for consumers.

Aspartame has been used for almost 30 years to sweeten carbonated beverages, desserts, dairy products and sweets and as a table-top substitute for sugar. Two hundred times sweeter than sugar, it is in thousands of products.

First synthesised in the 1960s, aspartame has weathered several controversies. The Ramazzini Foundation in Italy linked the sweetener to cancer in 2005–06 and again in 2010.1 Another study linked artificially sweetened soft drinks with increased incidence of preterm delivery.2 And a US study late last year linked aspartame to lymphoma and leukaemia.3 These studies were part of the review, says George Kass, deputy head of EFSA’s food ingredients unit.

A 15-member expert panel evaluated over 1000 studies for the review and concluded that studies do not suggest an increased risk for pre-term delivery, leukaemia, brain tumours or other cancers.

‘Some segment of consumers has always and will always find a cause for concern,’ notes toxicologist Nancy Szabo of the Burdock Group, a US regulatory consultant firm. ‘However, for the general population, at the current levels of approved exposure, such concerns should be minimal.’

According to EFSA, to reach the acceptable daily intake (ADI) for aspartame (40 mg/kg body weight), an adult weighing 60kg would have to drink 12 cans of a diet soft drink containing aspartame at the maximum permitted levels. 

EFSA has been particularly critical of the Italian lab; Kass says ‘there were some serious flaws with the design and interpretation of their data’. The Ramazzini Foundation rejects these criticisms. Fiorella Belpoggi, director of the institute, says the EFSA verdict is ‘a demonstration of arrogance’ and the agency ‘continues to ignore our data out of hand’, while ignoring failings in studies sponsored by industry. ‘I have no doubt about our results,’ Belpoggi adds.

Others are more positive about the review. ‘This is the first time EFSA has used human data to establish the safe level of consumption of aspartame,’ says Berna Magnuson, a food scientist at the University of Toronto, Canada. ‘The anti-aspartame activists continue to be very effective in scaring consumers with their theories and they are already working on responses to the EFSA report to discredit it. I will not be surprised if EFSA is called to assess aspartame safety again in a few years,’ she says. 


Related Content

Controversial sweetener declared safe

17 December 2013 News and Analysis

news image

European food safety panel concludes once more that aspartame is safe after a comprehensive review of the evidence

Report serves up food for thought for European agency

6 November 2013 News and Analysis

news image

European Food Safety Agency rebuffs accusations of loopholes in rules governing conflicts of interest of its experts

Most Read

Better batteries with pure lithium anodes

28 July 2014 Research

news image

Protective carbon nanosphere coating overcomes lithium problems, pointing the way to improved capacity

Takeover battle pushes Allergan to cut R&D jobs

28 July 2014 Business

news image

Besieged by serially acquisitive Valeant, the Botox maker will lay off 1500 staff to propel earnings growth

Most Commented

Bubble wrap could send lab costs packing

23 July 2014 Research

news image

Potential bubbles up across wide range of uses as storage and test vessels, especially for poor countries

Relativity behind mercury's liquidity

21 June 2013 Research

news image

First evidence that relativistic effects are indeed responsible for mercury's low melting point