Celgene buys into anticancer antibodies

US firms Celgene and OncoMed have tied up a deal to develop and commercialise biological therapies for cancer. The deal gives Celgene access to six antibody products in OncoMed’s pipeline, designed to target cancer stem cells rather than regular tumour cells. It also covers a small molecule development programme.

Celgene is paying $155 million (£95 million) in cash up front, as well as buying a $22.5 million slice of OncoMed’s equity. But the big money is in the potential payments that will be unlocked as the programmes meet developmental and regulatory milestones. The most advanced antibody, demcizumab, is currently in Phase 1b trials. If all goes to plan, the drug could net OncoMed $790 million, plus a share of any eventual sales. The other five programmes have milestone payments of $440–505 million attached, plus a potential $100 million for any small molecule that makes it through.

Related Content

Business roundup

30 June 2011 Business

news image

Industry news, July 2011

Business roundup

27 January 2012 Business

news image

Industry news, February 2012

Most Commented

How to print a crystal in 3D

17 April 2014 Research

news image

Rather than looking at a crystal on a screen, print it out and hold it in your hand

The sultan of synthesis

11 April 2014 Feature

news image

Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers