Generics give injectables a shot


Vial and syringe

Sterile injectables are difficult to manufacture well, but the market is growing © Shutterstock

Generics companies are scrabbling for footholds in the world of sterile injectable products. A rash of deals has seen India’s Lupin Pharmaceuticals and Aurobindo, as well as US firms Par Pharmaceuticals and Mylan, go for bigger slices of the multi-billion pound market.

On 3 February, Lupin agreed to buy Nanomi, an injectables specialist based in the Netherlands, for an undisclosed amount. In January, Aurobindo finalised a deal with Actavis to take over chunks of its European operations, including a platform to launch injectable products based on Actavis’s hospital sales infrastructure.

In the US, Par Pharmaceuticals’ $490 million (£300 million) buyout of injectables expert JHP Pharmaceuticals follows on from a string of similar deals last year, notably Mylan’s takeover of Agila injectables, worth up to $1.75 billion, bolstering Mylan’s position as a major injectables producer.

Injectables is an attractive growing market, linked to growth in complex biological drugs – particularly as generic biosimilar versions start to be approved. Most of these products are unsuitable for formulating as tablets, so need to be injected. Diabetes and cancer treatments are also commonly injected, and with ageing populations demand for these medicines is increasing steadily.

But manufacturing injectables is a tricky business, as shown by a steady stream of quality concerns, failed manufacturing inspections and ensuing product shortages. That means the barriers to entry are high – hence new players are buying their way in through acquisitions rather than starting from scratch.


Related Content

Hospira buyout is a shot in the arm for Pfizer’s biosimilars

12 February 2015 Business

news image

$17bn deal, intended to bolster sterile injectable and biologics capabilities, will be financed with existing cash and new de...

Megamerger brings Actavis into R&D race

25 February 2014 Business

news image

$25bn Forest Labs takeover will see generics giant take on patented products

Most Read

First pictures of hydrogen bonds unveiled

26 September 2013 Research

news image

Observation of intermolecular interactions in quinolines could help to settle the nature of this kind of bonding

Copper catalysis overcomes double bond trouble

3 July 2015 Research

news image

Stubbornly stable unactivated internal alkenes become chiral tertiary amine precursors

Most Commented

Collaboration, not competition

29 June 2015 Research

news image

Organic chemist E J Corey talks to Phillip Broadwith about awards, ambition and academic freedom

Z machine puts the squeeze on metallic deuterium

25 June 2015 Research

news image

Pressures similar to those at centre of the Earth forge metallic deuterium in step toward 80-year-old dream of creating metal...