Pre-childbirth solvent exposure raises breast cancer risk


The timing of exposure to organic solvents – such as those found in cleaning products and industrial chemicals – may affect breast cancer risks in women, according to a study from the US National Institute of Environmental Health Sciences.

Christine Ekenga and colleagues found that women exposed to organic solvents before having their first child had a higher risk of developing hormone-related breast cancer, that is promoted by the presence of oestrogen or progesterone.

The group used data from the Sister Study, a project following a cohort of over 50,000 women whose sisters have been diagnosed with breast cancer, all of whom were healthy at the time they enrolled. Questionnaires were used to monitor various risk factors, including potential exposure to organic solvents during work, and follow-up studies tracked whether they went on to develop breast cancer.

While lifetime exposure to solvents was found not to affect the overall breast cancer risk, the risk was found to be higher for women who had started to work with solvents before having their first child. This indicates the breasts could be more vulnerable to chemical exposure during the period of development after puberty but before childbirth. The group say women who are regularly exposed to organic solvents – for example medical technicians, cleaners and factory workers – should minimise their exposure using personal protective equipment.


Related Content

Targeting breast cancer

28 March 2014 Premium contentFeature

news image

Tamoxifen has been treating breast cancer for 40 years, but few would have predicted how much this drug would contribute to s...

The mothers of invention

24 February 2015 Managing Change

news image

Nina Notman profiles four researchers successfully balancing an academic career with family life

Most Read

US government science institute's one time police chief linked to campus meth lab

31 July 2015 News and Analysis

news image

Explosion injuring a member of the National Institute of Standards and Technology's security force uncovered methamphetamine ...

(–)-Jiadifenolide

27 July 2015 Organic Matter

news image

BRSM wonders what makes a route so good it becomes the last total synthesis of a complex target

Most Commented

Philae poses comet chemistry conundrum

30 July 2015 Research

news image

Historic mass spectra find 67P carries precursors to key biomolecules, but instruments detect different ones

(–)-Jiadifenolide

27 July 2015 Organic Matter

news image

BRSM wonders what makes a route so good it becomes the last total synthesis of a complex target