Genentech to buy breast cancer specialist Seragon


Roche subsidiary Genentech has agreed to pay $725 million (£422 million) up front, plus up to $1 billion in milestone payments, for fledgling biotech firm Seragon Pharmaceuticals. The deal gives Genentech access to Seragon’s pipeline of investigational breast cancer therapies that work by destroying oestrogen receptors on the surface of cancer cells.

Certain breast cancers rely on the hormone oestrogen to grow and spread. Seragon’s drug candidates are designed to eliminate the tumours’ ability to develop resistance to drugs that block oestrogen receptors (including tamoxifen) or interfere with its production (such as aromatase inhibitors).

Seragon was only formed as a company in 2013. It was spun out of Aragon Pharmaceuticals when that company sold its hormone-based prostate cancer treatment pipeline to Johnson and Johnson.


Related Content

J&J buys Aragon’s prostate cancer arm

22 August 2013 Business

news image

Hormone cancer specialist spins out other programmes before sale

Targeting breast cancer

28 March 2014 Premium contentFeature

news image

Tamoxifen has been treating breast cancer for 40 years, but few would have predicted how much this drug would contribute to s...

Most Read

Antimicrobial resistance will kill 300 million by 2050 without action

16 December 2014 News and Analysis

news image

UK report says resistance will cost global economy $100 trillion

Cutting edge chemistry in 2014

10 December 2014 Research

news image

We take a look back at the year's most interesting chemical science stories

Most Commented

A bad business

19 December 2014 Critical Point

news image

Targets and assessments can boost productivity at universities – but only if they do not stifle creativity and alienate the...

Chemistry behind the ‘blue man’ unlocked

1 November 2012 Research

news image

Biochemical model suggests that silver ions, not nanoparticles, cause a rare skin complaint