29 July 2013 Research
That’s a lot of boron!
Real-time biodistribution patterns of the COSAN derivatives
Researchers in Spain have come up with a way to track the biodistribution of a boron cluster complex used to prepare boron-carrier drugs for a prospectvie cancer treatment called boron neutron capture therapy (BNCT).
Drugs based on the boron cluster complex COSAN (cobaltabisdicarbollide) exploit the over-expression of membrane receptors in cancer cells to deliver therapeutic levels of 10B across the membrane. Although 10B is a stable isotope, when a beam of low-energy neutrons is applied to the cell, 10B captures a neutron and subsequently decays, releasing a high-energy α-particle and destroying the cell.
Radioiodination will make it possible to track the compounds
This article is free to access until 26 September 2014. Download it here:
14 January 2016 Research
Binding strengths of polymer–boron nitride nanotubes are higher than those reported for carbon nanotubes
27 April 2016 News and Analysis
Nearly 200 countries signed the global climate treaty that aims to limit temperature rises to ‘well below’ 2°C