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Counterintuitive thinking

27 November 2012 Review

Paradox: the nine greatest enigmas in science

Running rings around molecular wires

25 June 2012 Research

Polyynes stabilised with chemical loops could be turned into wires for molecular electronics

Molecular chaperones caught on film

23 March 2012 News Archive

Thousands of snapshots of chaperone proteins at work have given researchers a unique insight into how they function

Getting stuck in

29 November 2011  Premium contentFeature

Nature produces a wide variety of glues that outperform all synthetic adhesives. Michael Gross looks into this sticky subject

Anarchy in the proteome

29 July 2011  Premium contentFeature

15 years ago, the idea that proteins might be functional without a well-ordered 3D structure was heretical. But Michael Gross discovers, a little flexibility can go a long way

New hope for malaria drugs as sickle cell protection unravelled

3 May 2011 News Archive

Understanding how the sickle cell anaemia gene protects its carriers from malaria may lead to new therapies

Origin of life experiments revisited

21 March 2011 News Archive

Forgotten samples of Stanley Miller's add clues to the origin of life

The spiders' apprentices

30 November 2010  Premium contentFeature

For years scientists have tried and failed to artificially reproduce the properties of spider silk. Michael Gross untangles the latest strands of research

Kiss of death for cancer cells

31 October 2010 News Archive

Scientists have deciphered the surprising structure of the perforin pore, which delivers lethal enzymes that kill cancer cells in the body

Spinning around

28 April 2010  Premium contentFeature

Electron spin resonance is emerging as a valuable analytical tool with a wide range of uses. Michael Gross reports

What's bugging the bees?

28 January 2010  Premium contentFeature

Insecticides, pathogens, stress? Michael Gross reports on possible explanations for the mysterious vanishing of honeybee colonies

DNA to direct and switch off chemo

28 July 2009 News Archive

Researchers in the US have used DNA strands to target chemotherapy and switch it off if unwanted side effects appear

Bubble-wrapped frogs

29 May 2009 Feature

Tropical frogs create remarkable foams to protect their spawn. Exploration of the underlying chemistry has only just begun, as Michael Gross discovers

Quick-switching carbon nanotube displays

19 May 2009 News Archive

Chinese researchers have shown that thin carbon nanotube films can serve as incandescent displays that switch on and off faster than LCDs

Efficient solar cells could work in tandem

1 May 2009 News Archive

An efficient new dye-based solar energy system could built into a doubly-active solar cell

Light-guided hydrogels direct cell growth

2 April 2009 News Archive

Physical and chemical microenvironment of cells can be manipulated using light-responsive hydrogels

Is DNA nanotechnology coming of age?

30 March 2009  Premium contentFeature

DNA nanotechnology has moved a long way since its first public appearance in 1991 - and its first applications are already on the horizon, says Michael Gross

Capsules with flexi-pores open wide

19 March 2009 News Archive

Researchers have shown that a molecular capsule with flexible pores can admit over-size guest molecules.

Cracking wood gently

30 September 2008 News Archive

Ionic liquids and solid catalysts combine to hydrolyse cellulose without aggressive acids

Hot chillis evolved to kill fungi

11 August 2008 News Archive

Study confirms spicy capsaicinoids defend fruit from microbes

Light drives plastic motor

12 June 2008 News Archive

A plastic that stretches in response to light can drive an engine

Improving photodynamic cancer therapy

30 May 2008 News Archive

Chemists have developed new compounds that can help to focus the activity of light-activated drugs with pinpoint accuracy

Aluminium's vaccine boost explained

1 April 2008 News Archive

Researchers have shown how 'alum' adjuvants make vaccines more effective

Chemical wheel could boost computers

11 March 2008 News Archive

Researchers in Japan have created a molecular assembly that could allow 16 bit parallel processing

Sea cucumbers inspire switchable material

6 March 2008 News Archive

Composite can flip between rigid and flexible states - just like the skin of the sea-bed scavenger

Modified nanotubes catalyse fuel cell

29 February 2008 News Archive

Platinum nanoparticles boost methanol oxidation

Modified nanotubes catalyse fuel cell

27 February 2008 News Archive

Platinum nanoparticles boost methanol oxidation

Rubber that heals itself

20 February 2008 News Archive

A rubber-like material can mend itself when cut or broken

Nanofibre tape is sticky stuff

18 February 2008 News Archive

Surgeons and climbers could benefit from new materials inspired by gecko's feet

Machines get a taste for espresso

11 February 2008 News Archive

Nestlé researchers have developed a robot that can predict the taste of coffee within minutes

A DNA crane for molecular building sites

31 January 2008 News Archive

A DNA strand attached to the tip of an atomic force microscope can build nanoscale structures

Turning gas into fuel cheaply

23 January 2008 News Archive

Fuel cell converts methane to methanol at lower temperature and pressure

Chemists tame the uranyl ion

16 January 2008 News Archive

A new uranium compound sheds lights on how to make the element more manageable in future

Ice-cream without the crunch

14 January 2008 News Archive

Fragments of gelatin can suppress the growth of ice crystals in frozen food

Portable organs

20 December 2007  Premium contentFeature

A combination of medical research and engineering could bring an end to the era of putting precious human organs on ice to keep them alive for longer. Michael Gross reports

Haem's secret life as a hormone exposed

7 December 2007 News Archive

Best known as blood's oxygen carrier, haem may also be a signalling molecule

Flash memory enters another dimension

3 December 2007 News Archive

Enhanced data storage with layers of gold nanoparticles

Blood transfusion risk explained

8 October 2007 News Archive

Missing nitric oxide may be why banked blood is a risk to some patients

Grapevine genome reveals wine's flavour secrets

26 August 2007 News Archive

Genetic profile could help in breeding new disease-resistant or health-giving varieties

Goat antidote

23 July 2007 News Archive

Gram quantities of a potent chemical-weapon antidote have been produced in goats' milk

Predicting how proteins fold

6 July 2007 News Archive

Researchers have developed new ways of simulating the folding of membrane proteins, which could aid drug development

Cold chemistry

5 July 2007 News Archive

Chemical reactions at extremely low temperatures, for instance in interstellar clouds, can run at surprisingly fast rates

Virulence from the deep sea

3 July 2007 News Archive

Genetic traits of chemosynthetic bacteria living in the deep sea have evolved into virulence traits in common gut bacteria

Transistor tuned to ion channel

2 July 2007 News Archive

Living cells coupled to transistors pick up the cellular response to serotonin as an electronic signal.

A mirror for the moon

21 June 2007 News Archive

Researchers have coated an ionic liquid with a reflective surface, making it (almost) suitable for a Moon-based telescope

Further integration of micro fluidics and mass spec

17 May 2007 News Archive

Glass microchip combines microfluidic channels with a nanospray emitter for electrospray ionization mass spectrometry

Titan's tholins

11 May 2007 News Archive

Spectroscopic measurements used to study the formation of large and complex organic molecules making up the atmosphere on Saturn's moon

Protein printboard

2 May 2007 News Archive

'Molecular printboard' technique builds protein biochips with unprecedented control over binding specificity, strength, and orientation

Deadly beetles intercept bee's warnings

30 April 2007 News Archive

Parasitic beetles invade the hives of honeybees in America with the help of the bees' own alarm pheromone

Molecular trees bear fruit

27 April 2007  Premium contentFeature

Polymers that grow like trees have been around for nearly three decades. Now they are on the verge of realising their potential, as Michael Gross reports

Love sex intelligence

26 April 2007  Premium contentReview

Lust and love. Is it more than chemistry?

The actinides, not so unpredictable after all

28 March 2007 News Archive

Theoretical framework accounts for unexpected properties of the late actinides (plutonium, americium and curium)

Eat isotopes to live longer

22 March 2007 News Archive

Deuterium and carbon-13 could be used to suppress the ageing reactions attributed to reactive oxygen species

Nanowires go round the bend

9 March 2007 News Archive

Template spokes bend rigid nanowire into wheel

Nature's supramolecular chemistry

6 March 2007 News Archive

Molecular biology meets metal oxide chemistry.

The last retort

1 March 2007  Premium contentLast Retort

There are more than 140 million registered users on MySpace

Immune system guardian against HIV identified

23 February 2007 News Archive

Researchers surprised to find that active genes on X chromosomes are more heavily methylated than inactive versions.

X labelling springs a surprise

23 February 2007 News Archive

Researchers surprised to find that active genes on X chromosomes are more heavily methylated than inactive versions.

Nano-pumpkins fitted for drug delivery

12 February 2007 News Archive

Surface modification of polymerised nanocapsules.

Nanoparticles bond like atoms in a molecule

18 January 2007 News Archive

Hairy ball theorem used to get isotropic nanoparticles linking up in a chain.

Bioassays work on paper

16 January 2007 News Archive

Printing technique produces small volume reaction chambers for low-cost bioassays.

Fixing the nitrogen balance

10 January 2007 News Archive

New analysis of the global nitrogen cycle suggests nitrogen fixation and denitrification are closely coupled in space and time.

Nano-clots target tumours

8 January 2007 News Archive

Researchers have constructed nanoparticles that home in on tumours and partially block their blood supply

Is there any life out there?

20 December 2006  Premium contentReview

Astrobiology. A brief introduction

Ancient protein moonlights in the eye

12 December 2006 News Archive

Bacterial enzyme coopted for supporting role in vertebrate eye lens

Hydrogen generation mimics photosynthesis

5 December 2006 News Archive

Efficiency of splitting water with sunlight reaches new heights

Synthesis success after 30 years

28 November 2006 News Archive

Chemists finally make moenomycin antibiotic from scratch

Nanoribbons put electrons in a spin

15 November 2006 News Archive

Calculations predict that some graphene nanoribbons behave as half-metals, making them a useful material for spin-based electronics (spintronics).

Alzheimer's century

2 November 2006 News Archive

Researchers worldwide are commemorating the centenary of Alois Alzheimer's first description of the dementia named after him

Death sentences for microbes

18 October 2006 News Archive

Researchers have used linguistic analysis to create new antimicrobial agents.

Brief encounter

16 October 2006 News Archive

NMR spectroscopists have developed a method to observe the initial encounter between two proteins before they form a stable complex

Miniature microbicides

9 October 2006 News Archive

Combining the features of two types of antimicrobial in a minimalist design has generated an efficient low-budget antibiotic.

Imaging for the masses

3 October 2006 News Archive

Researchers have adapted mass spectrometry to image the distribution of molecules in tissues or membranes.

Alzheimer's alphabet

21 September 2006 News Archive

Discovery of the normal healthy function of proteins that malfunction in Alzheimer's disease points to possible treatments.

Any colour so long as it's green

19 September 2006 News Archive

New anti-microbial polymer coating can be applied from aqueous suspension.

Iron chelates beat cancer

18 September 2006 News Archive

Iron entrapment in cancer cells bypasses resistance to chemotherapy.

Selective shortcut

6 September 2006 News Archive

Simple catalyst speeds up the synthesis of a chiral protected building block used in complex syntheses.

Antibodies in the greenhouse

4 September 2006 News Archive

Producing immunoglobulins in plants could yield gram quantities of these precious proteins.

Branching out

30 August 2006  Premium contentReview

Dendrimers in medicine and biotechnology - new molecular tools

Around the world

25 August 2006  Premium contentFeature

The Earthwatch Institute, which has just celebrated its 35th birthday, supports vital research by dispatching fee-paying volunteers to project locations around the globe.

Biotronics branches out

24 August 2006 News Archive

Nanowire devices can communicate with individual nerve cells and their extensions.

Nanoparticle toxicity tested

16 August 2006 News Archive

The first direct in vivo comparison of nanoparticles with their equivalent bulk materials shows little difference in their toxic effects

Barcode for toxin sensors

14 August 2006 News Archive

Stripy nanowires detect different toxins or bioweapons

Catalyst cracks tough cellulose

13 July 2006 News Archive

Could straw furnish the fuel of the future?

Insecticide simplified

6 July 2006 News Archive

Structure-function analysis will help to tackle the growing problem of insecticide resistance.

Copper corrosion makes the print clock tick

27 June 2006 News Archive

A technique used to pinpoint the time at which new species of life evolved has been adapted to date historic prints.

Chemical origami

26 June 2006  Premium contentFeature

Sensors with molecular probes that fold around their targets, in combination with electrochemical detection, are being heralded as the ultimate user-friendly 'just add sample' device. Michael Gross reports.

New twists on catalysis

1 June 2006 News Archive

Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions

A physiological role for healthy prions

30 May 2006 News Archive

The healthy version of the scrapie pathogen helps regulate intracellular copper ion levels.

Precious platinum photographs

18 May 2006 News Archive

A photograph printed in platinum and then modified with the gum bichromate process, has sold for nearly $3 million at Sotheby's.

Chilling warnings on receding permafrost

2 May 2006 News Archive

The annual loss of around one per cent of the world's permafrost areas could trigger the release of even more greenhouse gases.

Arrays learn to multitask

27 April 2006 News Archive

US researchers have increased the information density of microarrays without further shrinking the dimensions of the spots.

Plant virus fixed with antennae

16 March 2006 News Archive

Researchers in the UK have coupled a virus with redox-active molecules, creating particles they say could be useful in nanoelectronics.

Chemists crack cocaine detection

2 March 2006 News Archive

Researchers, including two high school students and a Nobel laureate, have created a sensitive, simple, cocaine sensor.

A DNA switch for RNA folding

27 February 2006 News Archive

US researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will.

Chiral catalysis on a chip

1 February 2006 News Archive

Chiral catalysis and analytical separation of the resulting enantiomers can now be performed on a single chip.

Cupid's chemistry

26 January 2006 Feature

Scientists are beginning to make sense of romantic love through modern imaging techniques and a multidisciplinary approach. Michael Gross uncovers the method behind the madness

Grammatical analysis for protein annotation

9 January 2006 News Archive

A linguistic approach could revolutionise the analysis and annotation of complex proteome data, an Italian protein expert has argued.

Chemists queue up for Cuban collaboration

4 January 2006 News Archive

Chemists from UK and Cuban universities will meet in Havana next week to discuss the application of chemistry in the life sciences.

Nanoscience from a chemist's perspective

23 December 2005  Premium contentReview

Nanochemistry: a chemical approach to nanomaterials