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Pactamycin
29 May 2013 Totally Synthetic
Labelling a molecule 'inaccessible to synthesis' is a red rag to a bull, says Paul Docherty
Kingianin A
1 May 2013 Totally Synthetic
Paul Docherty faces his fears of frontier molecular orbital theory
Hyperforin
24 January 2013 Totally Synthetic
A flexible natural product synthesis is the key to later drug development
Flueggine A
2 January 2013 Totally Synthetic
Some exotic heterocyclic chemistry catches Paul Docherty's eye
Pentalenolactone A methyl ester
27 November 2012 Totally Synthetic
Paul Docherty revises a reaction he never could quite remember
Epicoccin G
31 October 2012 Totally Synthetic
Paul Docherty gets to grips with some thiodiketopiperazines
Prostaglandin F2α
1 October 2012 Totally Synthetic
Paul Docherty comes face to face with an old adversary
Amphidinolide F
29 August 2012 Totally Synthetic
Symmetry in natural products isn’t always so apparent
Marinomycin A
27 July 2012 Totally Synthetic
Faced with the term ‘polymer’, most people would consider man-made materials
Vincorine
1 July 2012 Totally Synthetic
Cage-structured natural products are some of the most appealing targets for organic chemists
atrop-Abyssomicin C
31 May 2012 Totally Synthetic
Natural products frequently have hard to pronounce and even harder to spell names, often of little meaning.
Hopeahainol A and hopeanol
30 April 2012 Totally Synthetic
This month's synthesis looks somewhat familiar
Indoxamycin B
31 March 2012 Totally Synthetic
It has always been the rearrangement reactions that did their best to elude my eye
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