Issue 14, 2003
From the journal:

Organic & Biomolecular Chemistry

Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

Martin G. Banwell,*a   Anna Bezos,b   Satish Chand,a   Gerd Dannhardt,c   Werner Kiefer,c   Ulrike Nowe,c   Christopher R. Parish,b   G. Paul Savaged  and  Holger Ulbrichc  

* Corresponding authors

a Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia
E-mail: mgb@rsc.anu.edu.au

b John Curtin School of Medical Research, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia

c Institut für Pharmazie, Johannes Gutenberg-Universität, Staudinger Weg 5, D-55099 Mainz, Germany

d CSIRO Molecular Science, Private Bag 10, Clayton South MDC, Victoria 3169, Australia

Abstract

Treatment of an equimolar mixture of stilbene 7 and cinnamyl alcohol 8 with silver carbonate in acetone–benzene afforded a ca. 2 : 1 : 2 : 1 mixture of the stilbenolignan (±)-aiphanol (1) and congeners 2–4 each of which show significant anti-angiogenic and COX-2 inhibitory properties.

Graphical abstract: Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B305106D
Article type
Communication
Submitted
09 May 2003
Accepted
13 Jun 2003
First published
23 Jun 2003

Org. Biomol. Chem., 2003,1, 2427-2429

Permissions

Request permissions

Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

M. G. Banwell, A. Bezos, S. Chand, G. Dannhardt, W. Kiefer, U. Nowe, C. R. Parish, G. Paul Savage and H. Ulbrich, Org. Biomol. Chem., 2003, 1, 2427 DOI: 10.1039/B305106D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements