Issue 2, 2004

Biogenetic speculation and biosynthetic advances

Abstract

Covering: the literature up to 2003

The present article highlights selected instances of the formulation of biogenetic schemes which over the past half century have contributed to our current understanding of the biosynthesis of secondary metabolites. These are mostly formed from a small number of primary precursors, which can often be identified by structural analysis. Representative examples of the role of speculation are discussed with particular emphasis on homo- and heterocyclic polyketides and amino acid derived products.

Graphical abstract: Biogenetic speculation and biosynthetic advances

Article information

Article type
Review Article
Submitted
10 Dec 2003
First published
23 Mar 2004

Nat. Prod. Rep., 2004,21, 224-248

Biogenetic speculation and biosynthetic advances

R. Thomas, Nat. Prod. Rep., 2004, 21, 224 DOI: 10.1039/B311022M

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