| In this section: | Fatty acids | Esters | Phospholipids | Test your knowledge | |
LipidsLipid is the collective name for fats, oils, waxes and fat-like molecules (such as steroids) found in the body. Their roles include:
The basic unit of lipids is a triglyceride, synthesised from glycerol (propane-1,2,3-triol) and fatty acids. Glycerol is a type of alcohol. Alcohols are organic compounds. Their molecules are characterised by hydroxyl groups, -OH. Glycerol is a trihydric alcohol, which means each molecule has three hydroxyl groups. Fatty acidsFatty acids are also organic compounds. Each fatty acid has a carboxylic acid (-COOH) group. Some fatty acids are saturated. These means all carbon-carbon bonds are single covalent bonds. Other fatty acids are unsaturated. This means that while most carbon-carbon bonds are single covalent bonds, some are double bonds. EstersAlcohols react with carboxylic acids to form esters R1OH + R2COOH As with the formation of glycosidic and peptide bonds, this is a condensation reaction. A water molecule splits out. The glycerol molecule has three hydroxyl groups. When one reacts with a fatty acid a monoglyceride forms. When two react with two fatty acid molecules a digylceride forms. And when three react with three fatty acid molecules a trigylceride forms.
Triglycerides formed between glycerol and unsaturated fatty acids are usually oils. Those formed with saturated acids are usually fats. PhospholipidsPhosphoric acid is an inorganic compound. Its molecular formula is H3PO4. Like fatty acids, it can react with alcohols to form esters (in this case, usually called phosphate esters). In phospholipids, one of the fatty acids of a triglyceride is substituted by a phosphate group.
Phospholipids have a key role in the structure and properties of cell membranes. Test your knowledge
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