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Communication
Org. Biomol. Chem., 2007, 5, 2753 - 2755, DOI: 10.1039/b708884c
Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product—a further simplification of the lactone region
Simon J. Shaw, Hugo G. Menzella, David C. Myles, Ming Xian and Amos B. Smith III
Analogues of discodermolide in which the complete C-1 to C-7 fragment is replaced with a coumarin moiety display equivalent potency to that of the natural product.
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