Issue 11, 2009
From the journal:

Organic & Biomolecular Chemistry

Two-directional cross-metathesis†

Annabella F. Newton,a   Stephen J. Roe,b   Jean-Christophe Legeay,a   Pooja Aggarwal,a   Camille Gignoux,a   Nicola J. Birch,b   Robert Nixon,c   Marie-Lyne Alcarazc  and  Robert A. Stockman*a  

* Corresponding authors

a School of Chemistry, University of Nottingham, Nottingham, UK
E-mail: robert.stockman@nottingham.ac.uk
Fax: +44 (0)115 9513564
Tel: +44 (0)115 9513252

b School of Chemistry, University of East Anglia, Norwich, UK

c AstraZeneca, Bakewell Road, Loughborough, UK

Abstract

Two-directional cross-metathesis of a range of α,ω dienes with a variety of electron deficient alkenes has been accomplished. It was found that the process is quite general and gives complete selectivity for the E,E-dienes, making this a very useful and high yielding protocol for two-directional chain elongation.

Graphical abstract: Two-directional cross-metathesis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B907720K
Article type
Communication
Submitted
16 Apr 2009
Accepted
20 Apr 2009
First published
28 Apr 2009

Org. Biomol. Chem., 2009,7, 2274-2277

Permissions

Request permissions

Two-directional cross-metathesis

A. F. Newton, S. J. Roe, J. Legeay, P. Aggarwal, C. Gignoux, N. J. Birch, R. Nixon, M. Alcaraz and R. A. Stockman, Org. Biomol. Chem., 2009, 7, 2274 DOI: 10.1039/B907720K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements