Issue 10, 1987

Base-specific photocleavage of DNA induced by nanosecond U.V. pulsed laser radiation or methylene blue sensitisation

Abstract

Excitation of DNA in neutral solution either with short-duration, intense pulses of excimer laser (248 nm) radiation or with low intensity red-ligh (633 nm) sensitisation by methylene blue causes cleavage of the DNA backbone selectively at guanine.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 751-752

Base-specific photocleavage of DNA induced by nanosecond U.V. pulsed laser radiation or methylene blue sensitisation

W. Blau, D. T. Croke, J. M. Kelly, D. J. McConnell, C. OhUigin and W. J. M. Van der Putten, J. Chem. Soc., Chem. Commun., 1987, 751 DOI: 10.1039/C39870000751

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