4th Novalix Conference - Biophysics in Drug Discovery

6 June 2017 13:00 - 9 June 2017 13:00, Strasbourg, France


Introduction
For the fourth time, NovAliX is organising its Biophysics in Drug Discovery Conference. This new edition will cover current hot topics including integral membrane proteins (Special Focus of the Conference).

As last year, the venue will be the Hilton Strasbourg.

The use of biophysical methods in drug discovery is rapidly increasing and the field is in constant evolution, as documented in a recent article: "Biophysics in drug discovery: impact, challenges and opportunities." Renaud JP, Chung CW, Danielson UH, Egner U, Hennig M, Hubbard RE, Nar H. Nat. Rev. Drug Discov. 2016 Oct; 15(10): 679-698. Many pharmaceutical companies have set up in-house biophysical platforms to speed up the target-to-candidate process and improve the quality of small-molecule therapeutics through a better understanding of their interactions with their targets. Academic labs involved in early-stage drug discovery also heavily rely on biophysical techniques.

The fourth edition of the conference intends again to bring together biophysicists and medicinal chemists, the synergy between their disciplines being key to deliver better drugs on a shorter timeline.

This year, the Scientific Programme will include the following sessions :

Biophysical Techniques for the Study of Integral Membrane Proteins (GPCRs, Ion Channels, Transporters and others)
Detecting Allosteric Effectors / Inhibitors / Modulators
IDPs (Intrinsically Disordered Proteins) and the Dark Proteome
Recent Advances in FBDD [including challenging targets and HTS - FBS (fragment-based screening) combinations]
Recent Advances in NMR [including NMR as a (ligand co-)structure determination technology]
Characterisation and Optimisation of Antibodies and Relatives [antibody fragments, minibodies, nanobodies, bi- or tri-specific antibodies, ADCs, hybrid Ab-targeted protein fusions, alternate scaffolds and alternate scaffold conjugates (affinity drug conjugates), ...]

We are pleased to announce the following Keynote Lectures: Alain Beck (Pierre Fabre, France), Jean-Pierre Changeux (Collège de France & Institut Pasteur, France) and Dan Erlanson (Carmot Therapeutics, United States).

As for the previous editions, the Scientific Programme will be completed by Exhibitor short presentations, a Poster Session and a Commercial Exhibition.
Speakers
Sponsorship & supporting organisations
Venue
Hilton Strasbourg

Hilton Strasbourg, 1 Avenue Herrenschmidt, Strasbourg, 67000 , France

Committee
  • Dr Jean-Paul RENAUD NovAliX & RiboStruct, Illkirch, France
  • Dr Jim BRYSON Bristol-Myers-Squibb R&D, New York, United States
  • Dr Chun-wa CHUNG GlaxoSmithKline, Stevenage, United Kingdom
  • Prof. Helena DANIELSON Uppsala University, Uppsala, Sweden
  • Dr Ursula EGNER Bayer HealthCare, Berlin, Germany
  • Dr Michael HENNIG leadXpro AG, Villigen, Switzerland
  • Dr Geoff HOLDGATE AstraZeneca, Macclesfield, United Kingdom
  • Prof. Rod HUBBARD University of York & Vernalis, Cambridge, United Kingdom
  • Dr Sandra JACOB Novartis Institutes for Biomedical Research, Basel, Switzerland
  • Dr Herbert NAR Boehringer Ingelheim, Biberach, Germany

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