Integrin Targeted Drug Discovery

28 March 2019 09:00-17:00, London, United Kingdom


Introduction
Synopsis
Integrins are heterodimeric, transmembrane receptors that function in cell adhesion and signalling. They are central to many disease states, including cancer, thrombosis, multiple sclerosis and Crohn’s disease. Integrin targeted therapeutics have been under investigation for some time, but few compounds have made it to/ remained on the market due to side effects or lack of efficacy. Given the more recent structural insights, better understanding of downstream pathways, and potential application to a range of therapeutic areas, there has been a resurgence of interest in integrin inhibitors. This symposium will bring together researchers in this area to provide both a historical overview of the area and recent progress in designing the next generation of integrin inhibitors.

Who should attend
Scientists from industry and academia, including medicinal and computational chemists.

Features of the Meeting
Therapeutic targets for integrins
Targeting different RGD recognising integrins
Drug discovery, medicinal chemistry and structure-based design
Plenary speakers, poster session and trade exhibition

Full Programme
The full programme may be viewed in the second announcement, which is available for download.

Call for Abstracts
Applications for oral and poster presentations are welcomed. Posters will be displayed throughout the day, and the closing date has been extended to 7th February.

Registration
Registration is open and fees for payments received by 24th February are:
£120 RSC member
£150 Non-member
  £60 RSC student* member

Late rates for payments received from 25th February onwards:
£30 Late payment fee to be added to the above standard rates

Member is paid-up member of the RSC.

* Student is undergraduate or post-graduate (not post-doc), and does not apply to students in paid employment.
Member is paid-up member of the RSC.

Some student bursaries are available (to assist with registration fee, travel and accommodation). 

Exhibition
A relevant trade exhibition will add value to the symposium.   The exhibition will be held in the same room as the catering (refreshments and lunch) and posters, and the exhibition package costs £530 and includes:
- chair and table
- electrical access and wi-fi access
- one full delegate attendance.
Those companies wishing to have a trade stand should register an interest with the secretariat.  

A delegate pack insert may be booked at £175 - no more than two pages of A4 fixed together.

Venue and Travel
The symposium will be held in the Science and Fish Rooms, Royal Society of Chemistry at Burlington House, Piccadilly, London, W1J 0BA, UK.  Situated in central London, the RSC is easily accessible by public transport, and close to Green Park tube station.

Sponsors
Sponsors are encouraged to support this event, which will help us to offer inexpensive registration fees to young chemists.
Speakers
  • Dermot Cox Royal College of Surgeons in Ireland, Ireland
  • Daria Giacomini University of Bologna, Italy
  • Simon Goodman formerly of Preclinical Oncology, Merck Serono, Germany
  • Prof Dr Horst Kessler Technical University of Munich, Germany
  • Helen Sheldrake University of Bradford, United Kingdom
  • Luciana Marinelli University of Naples, Italy
  • Thomas McInally University of Nottingham, United Kingdom
  • Kate Moore Barts Cancer Institute, United Kingdom
  • Giovanna Musco Ospedale San Raffaele, Italy

Sponsorship & supporting organisations
Venue
The Royal Society of Chemistry

Science and Fish Rooms, The Royal Society of Chemistry, Burlington House, Piccadilly, London, W1J 0BA, United Kingdom

Committee
Organised by
RSC-BMCS
Contact information
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