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Journal articles made easy: Detecting strep throat using mass spectrometry


This article looks at detecting strep throat bacterium using touch spray mass spectrometry. It will help you understand the research the journal article is based on, and how to read and understand journal articles. The research article was originally published in our Analyst journal. 


1.   Gieseker, K. E., Roe, M. H., MacKenzie, T. & Todd, J. K. Evaluating the American Academy of Pediatrics diagnostic standard for Streptococcus pyogenes pharyngitis: backup culture versus repeat rapid antigen testing. Pediatrics111, e666-e670 (2003).

2.   Clerc, O. & Greub, G. Routine use of point‐of‐care tests: usefulness and application in clinical microbiology. Clinical Microbiology and Infection16, 1054-1061 (2010).

3.   Jarmusch, A. K., Pirro, V., Kerian, K. S. & Cooks, R. G. Detection of strep throat causing bacterium directly from medical swabs by touch spray-mass spectrometry. Analyst139, 4785-4789 (2014).

4.   Eberlin, L. S., Ferreira, C. R., Dill, A. L., Ifa, D. R. & Cooks, R. G. Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids1811, 946-960 (2011). 

5.   Hamid, A. M., Jarmusch, A. K., Pirro, V., Pincus, D. H., Clay, B. G., Gervasi, G. & Cooks, R.G. Rapid Discrimination of Bacteria by Paper Spray Mass Spectrometry. Analytical chemistry (2014).

6.   Sauer, S. & Kliem, M. Mass spectrometry tools for the classification and identification of bacteria. Nature Reviews Microbiology8, 74-82 (2010).

7.   Badu-Tawiah, A. K., Eberlin, L. S., Ouyang, Z. & Cooks, R. G. Chemical aspects of the extractive methods of ambient ionization mass spectrometry. Annual review of physical chemistry64, 481-505 (2013).

8.   Kerian, K. S., Jarmusch, A. K. & Cooks, R. G. Touch spray mass spectrometry for in situ analysis of complex samples. Analyst (2014).

9.   Liu, J., Wang, H., Manicke, N. E., Lin, J.-M., Cooks, R. G. & Z. Ouyang. Development, characterization, and application of paper spray ionization. Analytical chemistry82, 2463-2471 (2010).

10. Bergeron, M. G. et al. Rapid Detection of Group B Streptococci in Pregnant Women at Delivery. New England Journal of Medicine343, 175-179, doi:doi:10.1056/NEJM200007203430303 (2000).

11.  Bosker, W. M. & Huestis, M. A. Oral fluid testing for drugs of abuse. Clinical chemistry55, 1910-1931 (2009).

12.  Di Corcia, D. et al. Determination of pharmaceutical and illicit drugs in oral fluid by ultra-high performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography B (2013).


Journal articles made easy are journal articles from a range of Royal Society of Chemistry journals that have been re-written into a standard, accessible format. They contain links to the associated Chemistry World article, ChemSpider entries, related journal articles, books and Learn Chemistry resources such as videos of techniques, and resources on theory and activities. They should facilitate students understanding of scientific journal articles and how to extract and interpret the information in them.