From Learn Chemistry Wiki
- Main ChemSpider page
- Molecular formula: C2H2Cl2O2
- Molar mass: 128.942
- CAS Registry Number: 79-43-6
- Appearance: Dichloroacetic acid, 99%; Dichloroacetic acid, 99+%; Dichloroacetic acid, 99%; Dichloroacetic acid, 99+%; colourless liquid with a pungent odour
- Melting point: 9.7 °C
- Boiling point: 194 °C
- Solubility: Water, 1e+006 mg/L (20 deg C)
- Safety sheet: Not available
- Spectra: ChemSpider (IR), NMRShiftDB 13C NMR, Massbank MS (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20), also check on SDBS. Add Spectra (Help).
Dichloroacetic acid, often abbreviated DCA, is the chemical compound with formula CarbonCHydrogenHChlorineCl2Carboxylic acidCOOH. It is an acid, an analogue of acetic acid, in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. The salts and esters of dichloroacetic acid are called dichloroacetates. Salts of DCA have been studied as potential drugs because they inhibit the enzyme pyruvate dehydrogenase kinase.
Although preliminary studies have shown DCA can slow the growth of certain tumors in animal studies and in vitro studies, "Available evidence does not support the use of DCA for cancer treatment at this time."
Dichloroacetic acid (IUPAC Name); 2,2-Dichloro-acetic acid; Dichloro acetic acid
Please add any relevant references here.