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- Molecular formula: C6H1118FO5
- Molar mass: 181.150
- CAS Registry Number: Not available
- Appearance: Not available
- Melting point: Not available
- Boiling point: Not available
- Solubility: Not available
- Safety sheet: Not available
- Spectra: Check on SDBS. Add Spectra (Help).
Fludeoxyglucose (18F) (INN), or fludeoxyglucose F 18 (USAN and USP), also commonly called fluorodeoxyglucose and abbreviated [18F]FDG, 18F-FDG or FDG, is a radiopharmaceutical used in the medical imaging modality positron emission tomography (PET). Chemically, it is 2-deoxy-2-(18F)fluoro-D-glucose, a glucose analog, with the positron-emitting radionuclide fluorine-18 substituted for the normal hydroxyl group at the C-2 position in the glucose molecule.
The uptake of 18F-FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types of tissue metabolism. After 18F-FDG is injected into a patient, a PET scanner can form two-dimensional or three-dimensional images of the distribution of 18F-FDG within the body.
Since its development in 1976, 18F-FDG had a profound influence on research in the neurosciences. The subsequent discovery 1980 that 18F-FDG accumulates in tumors underpins the evolution of PET as a major clinical tool in cancer diagnosis. 18F-FDG is now the standard radiotracer used for PET neuroimaging and cancer patient management.
2-Deoxy-2-(~18~F)fluoro-alpha-D-glucopyranose (IUPAC Name); 2-(fluoro-(18)F)-2-deoxy-alpha-glucopyranose; 2-deoxy-2-((18)F)fluoro-alpha-D-glucopyranose; 2-deoxy-2-((18)F)fluoro-alpha-D-glucose; 2-deoxy-2-(18f)fluoro-d-glucose; 2-deoxy-2-(fluoro-(18)F)-alpha-D-glucopyranose; FDG; Flucis; Fludeoxyglucose (F18); Fludeoxyglucose F 18; Fludeoxyglucose F18; Fludeoxyglucose(18F)
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