RSC Biomolecular Sciences
Exploiting Chemical Diversity for Drug Discovery
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DOI: 10.1039/9781847552556
Paul A Bartlett (Editor), Michael Entzeroth (Editor)
ISBN (online): 978-1-84755-255-6
ISBN (print): 978-0-85404-842-7
Copyright: 2006
Table of Contents
| Title | Page | |
 Front Matter
DOI: 10.1039/9781847552556-FP001 (66Kb) |
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Preface
DOI: 10.1039/9781847552556-FP005 (37Kb) |
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Acknowledgements
DOI: 10.1039/9781847552556-FP009 (16Kb) |
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Contents
DOI: 10.1039/9781847552556-FP011 (59Kb) |
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Contributors
DOI: 10.1039/9781847552556-FP023 (32Kb) |
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The Use of Polymer-Assisted Solution-Phase Synthesis and Automation for the High-Throughput Preparation of Biologically Active Compounds
DOI: 10.1039/9781847552556-00001 (1Mb) |
1 | Full Access |
| Accelerated Chemistry: Microwave, Sonochemical, and Fluorous Phase Techniques | 33 | License Access |
| Biosynthesis of "Unnatural" Natural Products | 55 | License Access |
| Combinatorial Synthetic Design: The Balance of Novelty and Familiarity | 91 | License Access |
| Compound Collections: Acquisition, Annotation, and Access | 112 | License Access |
| Chemical Diversity: Definition and Quantification | 137 | License Access |
| Focused Libraries: The Evolution in Strategy from Large-Diversity Libraries to the Focused Library Approach | 161 | License Access |
| Translating Peptides into Small Molecules | 184 | License Access |
| High-Density Plates, Microarrays, Microfluidics | 201 | License Access |
| The Use of Genetically Engineered Cell-Based Assays in in-vitro Drug Discovery | 233 | License Access |
| The Use of Genetically Engineered Cell-Based Assays in in-vitro Drug Discovery | 247 | License Access |
| NMR-Based Screening: A Powerful Tool in Fragment-Based Drug Discovery | 263 | License Access |
| Screening Chemical Microarrays: Methods and Applications | 291 | License Access |
| Operational Developments in Chemistry | 313 | License Access |
| Concepts for In Vitro Profiling: Drug Activity, Selectivity and Liability | 336 | License Access |
| In Silico Surrogates for In Vivo Properties: Profiling for ADME and Toxicological Behavior | 364 | License Access |
| Uses of High Content Screening in Chemical Optimization | 386 | License Access |
| Subject Index | 405 | License Access |
