RSC Biomolecular Sciences
Therapeutic Oligonucleotides
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DOI: 10.1039/9781847558275
Jens Kurreck (Editor)
ISBN (online): 978-1-84755-827-5
ISBN (print): 978-0-85404-116-9
Copyright: 2008
Table of Contents
| Title | Page | |
 Front matter
DOI: 10.1039/9781847558275-FP001 (74Kb) |
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Preface
DOI: 10.1039/9781847558275-FP005 (43Kb) |
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Contents
DOI: 10.1039/9781847558275-FP009 (71Kb) |
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Chapter 1. The Role of Backbone Modifications in Oligonucleotide-Based Strategies
DOI: 10.1039/9781847558275-00001 (8Mb) |
1 | Full Access |
| Chapter 2. Genasense (G3139): An Antisense Bcl-2 Oligodeoxyribonucleotide with Substantial Clinical Activity and a Complex Mechanism of Action | 23 | License Access |
| Chapter 3. Antisense Morpholino Oligomers and Their Peptide Conjugates | 43 | License Access |
| Chapter 4. Peptide–Peptide Nucleic Acid Conjugates for Modulation of Gene Expression | 80 | License Access |
| Chapter 5. Locked Nucleic Acid: Properties and Therapeutic Aspects | 103 | License Access |
| Chapter 6. Immune Stimulatory Oligonucleotides | 142 | License Access |
| Chapter 7. Decoy Oligodeoxynucleotides to Treat Inflammatory Diseases | 163 | License Access |
| Chapter 8. AS1411: Development of an Anticancer Aptamer | 189 | License Access |
| Chapter 9. Spiegelmer NOX-E36 for Renal Diseases | 200 | License Access |
| Chapter 10. Strategies for the Delivery of Oligonucleotides in vivo | 226 | License Access |
| Chapter 11. Lipid-Mediated in vivo Delivery of Small Interfering RNAs | 241 | License Access |
| Chapter 12. Vector-Mediated and Viral Delivery of Short Hairpin RNAs | 267 | License Access |
| Chapter 13. Development of an RNAi-Based Gene Therapy against HIV-1 | 296 | License Access |
| Chapter 14. RNA Based Therapies for Treatment of HIV Infection | 316 | License Access |
| Subject Index | License Access |
