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The Analyst

The home of high impact research in analytical, bioanalytical and detection science.




Communication

Analyst, 2004, 129, 503 - 504, DOI: 10.1039/b405242k


Very high pressure HPLC with 1 mm id columns

Luis A. Colón, José M. Cintrón, Jason A. Anspach, Adam M. Fermier and Kelly A. Swinney


Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.