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The Analyst

The home of high impact research in analytical, bioanalytical and detection science.




Tutorial Review

Analyst, 2006, 131, 459 - 473, DOI: 10.1039/b515874e


An introduction to thiol redox proteins in the endoplasmic reticulum and a review of current electrochemical methods of detection of thiols

Jaanus Kruusma, Adam M. Benham, J. A. Gareth Williams and Ritu Kataky


This aim of this paper is to expound the complexity of thiol redox systems in the endoplasmic reticulum of eukaryotic cells to the electroanalytical community. A summary of the state of the art in electrochemical methods for detection of thiols gives an insight into the challenges that need to be addressed to bridge the disparity between current analytical techniques and applications in a real biological scenario.

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