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Journal of the Chemical Society, Chemical Communications


Journal of the Chemical Society, Chemical Communications was published between 1972 - 1995.

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Paper

J. Chem. Soc., Chem. Commun., 1978, 985 - 986, DOI: 10.1039/C39780000985


Synthesis of the butterfly compound (E,E)-10-hydroxy-3,7-dimethyldeca-2,6-dienoic acid

F. W. Sum and Larry Weiler


The title compound was synthesized by alkylation of the dianion of methyl acetoacetate, and lithium dimethylcuprate addition to the enol phosphate of the alkylated -keto esters (2) and (6) to produce the tri-substituted -unsaturated esters (4) and (7) in a stereoselective manner.