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Chem. Commun., 2005, 4432 - 4434, DOI: 10.1039/b504128g

Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates

Hari M. R. Gardimalla, Deendayal Mandal, Philip D. Stevens, Max Yen and Yong Gao

Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.

Graphical abstract image for this article (ID: b504128g)