RSC Publishing


Publishing

 

Cover image for Chemical Communications, select for current issue

Chemical Communications

Urgent high quality communications from across the chemical sciences.



Subscribers

  • PDF
  • HTML article

Non-subscribers

Free access



Communication

Chem. Commun., 2009, 5615 - 5617, DOI: 10.1039/b913693b

High temperature zincation of functionalized aromatics and heteroaromatics using TMPZnCl·LiCl and microwave irradiation

Marc Mosrin, Gabriel Monzon, Tomke Bresser and Paul Knochel

A wide range of functional aryl and heteroaryl zinc reagents have been efficiently prepared via regio- and chemoselective zincation using TMPZnCl·LiCl and microwave irradiation. Sensitive functional groups like esters are compatible with the high temperatures of the reactions. The resulting zinc species undergo a number of subsequent reactions, providing highly functionalized aromatics and heteroaromatics in high yields.

Graphical abstract image for this article (ID: b913693b)