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Chem. Commun., 2002, 2062 - 2063, DOI: 10.1039/b205631c


A parity code interpretation of nucleotide alphabet composition

Dónall A. Mac Dónaill


The purine–pyrimidine and hydrogen donor–acceptor patterns governing nucleotide recognition are shown to correspond formally to a digital error-detecting (parity) code, suggesting that factors other than physicochemical issues alone shaped the natural nucleotide alphabet.

Graphical abstract image for this article  (ID: b205631c)