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Chem. Commun., 2004, 168 - 169, DOI: 10.1039/b314358a

Intramolecular SN2 cyclization of an alkyllithium species onto a methoxy allyl ether is syn selective

Thomas E. La Cruz and Scott D. Rychnovsky

The preference for syn- or anti-addition of an intramolecular SN2 cyclization of an alkyllithium species onto a methoxy allyl ether has been proven unequivocally to take place by a syn SN2 mechanism.

Graphical abstract image for this article (ID: b314358a)