_tcm18-11397.gif )
Urgent high quality communications from across the chemical sciences.
Communication
Chem. Commun., 2005, 4821 - 4823, DOI: 10.1039/b509366j
Organocatalytic asymmetric
-bromination of aldehydes and ketonesSøren Bertelsen, Nis Halland, Stephan Bachmann, Mauro Marigo, Alan Braunton and Karl Anker Jørgensen
The first organocatalytic enantioselective
-bromination of aldehydes and ketones is presented; a C2-symmetric diphenylpyrrolidine catalyst afforded the -brominated aldehydes in good yields and up to 96% ee, while ketones were -brominated by a C2-symmetric imidazolidine in up to 94% ee; furthermore, the organocatalytic enantioselective -iodination of aldehydes is also demonstrated to proceed with up to 89% ee.
RSS feed
