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Chem. Commun., 2006, 2774 - 2776, DOI: 10.1039/b603438a

Synthesis of well-defined hydrogel networks using Click chemistry

Michael Malkoch, Robert Vestberg, Nalini Gupta, Laetitia Mespouille, Philipe Dubois, Andrew F. Mason, James L. Hedrick, Qi Liao, Curtis W. Frank, Kevin Kingsbury and Craig J. Hawker

New PEG-based hydrogel materials have been synthesized by Click chemistry and shown to result in well-defined networks having significantly improved mechanical properties; the selectivity of the azide/acetylene coupling reaction also allows for the incorporation of various additives and functional groups leading to chemical tailoring of the hydrogels.

Graphical abstract image for this article (ID: b603438a)