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Communication
Chem. Commun., 2007, 507 - 509, DOI: 10.1039/b611502k
One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael–aldol reaction
Hao Li, Jian Wang, Timiyin E-Nunu, Liansuo Zu, Wei Jiang, Shaohua Wei and Wei Wang
A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael–aldol reaction of
,
-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.
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