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Chem. Commun., 2006, 5009 - 5011, DOI: 10.1039/b613073a

Exploring cocrystal–cocrystal reactivity via liquid-assisted grinding: the assembling of racemic and dismantling of enantiomeric cocrystals

Tomislav Frii, László Fábián, Jonathan C. Burley, William Jones and W. D. Samuel Motherwell

The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal–cocrystal reactions.

Graphical abstract image for this article (ID: b613073a)