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Chem. Commun., 2007, 2747 - 2749, DOI: 10.1039/b703764c

Optimized pH-responsive cyanine fluorochromes for detection of acidic environments

Scott A. Hilderbrand and Ralph Weissleder

Modulation of pH-responsive cyanine dye pKa values via heteroatom substitution allows for design of fluorescent reporters that are tuned for potential imaging of biologically relevant acidic environments.

Graphical abstract image for this article (ID: b703764c)