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Chem. Commun., 2009, 7482 - 7484, DOI: 10.1039/b901889a


Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes

Gavin Collie, Anthony P. Reszka, Shozeb M. Haider, Valérie Gabelica, Gary N. Parkinson and Stephen Neidle


Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.

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