Issue 25, 2009
From the journal:

Chemical Communications

Antibacterial cyclic d,l-α-glycopeptides†

Leila Motiei,a   Shai Rahimipour,a   Desiree A. Thayer,a   Chi-Huey Wonga  and  M. Reza Ghadiri*a  

* Corresponding authors

a Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, USA
E-mail: ghadiri@scripps.edu
Fax: +1 858-784-2798
Tel: +1 858-784-2700

Abstract

We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic D,L-α-glycopeptides bearing D-glucosamine (GlcNH2), D-galactose (Gal), or D-mannose (Man) glycosyl side chains.

Graphical abstract: Antibacterial cyclic d,l-α-glycopeptides

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Article information

DOI
https://doi.org/10.1039/B902455G
Article type
Communication
Submitted
05 Feb 2009
Accepted
20 Apr 2009
First published
29 May 2009

Chem. Commun., 2009, 3693-3695

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Antibacterial cyclic D,L-α-glycopeptides

L. Motiei, S. Rahimipour, D. A. Thayer, C. Wong and M. R. Ghadiri, Chem. Commun., 2009, 3693 DOI: 10.1039/B902455G

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