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Communication

Chem. Commun., 2009, 7297 - 7299, DOI: 10.1039/b913520k


Highly enantioselective synthesis of tertiary alcohols: C2-symmetric N,N-dioxide-Sc(III) complex promoted direct aldol reaction of -ketoesters and diazoacetate esters

Fei Wang, Xiaohua Liu, Yulong Zhang, Lili Lin and Xiaoming Feng


A C2-symmetric N,N-dioxide-Sc(III) complex has been developed to promote the asymmetric catalytic aldol reaction of -ketoesters and diazoacetate esters to afford tertiary alcohols in good yields with excellent enantioselectivities.

Graphical abstract image for this article  (ID: b913520k)