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Chem. Commun., 2010, 46, 237 - 239, DOI: 10.1039/b915589a


Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

Michael S. Bereman, Daniel L. Comins and David C. Muddiman


Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a 5-fold increase in electrospray response from both a standard and complex mixture.

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