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Article citation: Theres Ramenda, Chem. Commun., 2009, DOI: 10.1039/b916075b

Radiolabelling of proteins with fluorine-18 via click chemistry

Theres Ramenda, Torsten Kniess, Ralf Bergmann, Jörg Steinbach and Frank Wuest

The study describes for the first time the application of Cu(I)-mediated 1,3-dipolar [3+2]cycloaddition for the labelling of proteins with the short-lived positron emitter fluorine-18 as exemplified with azide-functionalized human serum albumin (HSA).

Graphical abstract image for this article (ID: b916075b)