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Chem. Commun., 2010, 46, 454 - 456, DOI: 10.1039/b917758b


Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

José Alemán, Virginia del Solar and Carmen Navarro-Ranninger


An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.

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