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Chem. Commun., 2010, 46, 103 - 105, DOI: 10.1039/b918611e

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

Lynda Cosgrave, Marc Devocelle, Robert J. Forster and Tia E. Keyes

The capacity of ruthenium polypyridyl complexes as probes for combined confocal luminescence and resonance Raman imaging, enabled by their large Stokes shift, is demonstrated for a novel membrane sensitive Ru(II) polypyridyl peptide. Confocal luminescence and resonance Raman imaging provides complementary information about the membrane phospholipid regions of the cell and the location of the dye within the cell.

Graphical abstract image for this article (ID: b918611e)