_tcm18-11397.gif )
Urgent high quality communications from across the chemical sciences.
Subscribers
Non-subscribers
- Purchase article PDF [£30 + taxes]
- Purchase article PDF member offer [£5 + taxes]
Free access
Communication
Chem. Commun., 2010, 46, 466 - 468, DOI: 10.1039/b918626c
Cyanative alkene–aldehyde coupling: Ni(0)–NHC–Et2AlCN mediated chromanol synthesis with high cis-selectivity at room temperature
Chun-Yu Ho
Described are several classes of Ni(0) mediated cyanative alkene–aldehyde coupling reactions, providing 6-membered cores, which complement existing cyclization technology in several respects. Et2AlCN was used as both a cyclization accelerator and CN source. The NHC ligand may have a positive effect in differentiating reductive elimination and syn-
-hydride elimination.
RSS feed