Communication

Chem. Commun., 2010, 46, 625 - 627, DOI: 10.1039/b918964e

---

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes

Alexandro Membrino, Manikandan Paramasivam, Susanna Cogoi, Jawad Alzeer, Nathan W. Luedtke and Luigi E. Xodo

---

Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.

About this Journal

• Journal Home
• About the Journal

Read the Journal

• Advance Articles
• Browse Issues
• Search RSC Journals
• RSC Prospect Structure Search
• E-Alerts Service
• RSS feed

ReSourCe

• Submit an Article
• Author Guidelines
• Ethical Guidelines
• Copyright & Permissions
• Referee Report Forms

Explore the Journal

• Hot Articles
• Cover Gallery
• Top 10
• People and Contacts

Customer Services

• Subscriptions
• Advertising
• Librarians

Tools