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Chem. Commun., 2010, 46, 589 - 591, DOI: 10.1039/b919744c

Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs)

Karunakaran A. Kalesh, Lay Pheng Tan, Kai Lu, Liqian Gao, Jigang Wang and Shao Q. Yao

Synthesis of a novel unnatural amino acid (2-FMPT) for the solid-phase synthesis of peptide-based probes suitable for target-specific activity-based profiling of protein tyrosine phosphatases from crude proteomes is reported.

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