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Communication

Chem. Commun., 2010, 46, 153 - 155, DOI: 10.1039/b921000h


Total synthesis of largamide H

Shuo Liang, Zhengshuang Xu and Tao Ye


Total synthesis of largamide H has been completed, utilising the oxidative elimination reaction of enantiomerically pure 2-amino-3-(phenylselenyl)butanoic acid residues to stereospecifically install both (Z)- and (E)-2,3-dehydro-2-aminobutanoic moieties.

Graphical abstract image for this article  (ID: b921000h)