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Dalton Transactions

The international journal for inorganic, organometallic and bioinorganic chemistry




Communication

Dalton Trans., 2005, 654 - 655, DOI: 10.1039/b416040a


A glucosamine–dipicolylamine conjugate of 99mTc(I) and 186Re(I) for use in imaging and therapy

Tim Storr, Cara L. Fisher, Yuji Mikata, Shigenobu Yano, Michael J. Adam and Chris Orvig


The synthesis and metal complexation of a glucosamine-appended 2,2-dipicolylamine ligand to the tricarbonyls of 99mTc and 186Re is described; the ligand was found to bind in a tridentate fashion with the glucosamine function remaining pendant, and the 99mTc complex was found to exhibit exceptional stability towards in vitro ligand exchange experiments.

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