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Dalton Transactions

The international journal for inorganic, organometallic and bioinorganic chemistry




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Dalton Trans., 2010, 39, 1182 - 1184, DOI: 10.1039/b920786b


Markedly different cytotoxicity of the two enantiomers of C2-symmetrical Ti(IV) phenolato complexes; mechanistic implications

Cesar M. Manna and Edit Y. Tshuva


The two enantiomers of a member of the highly active C2-symmetrical bis(isopropoxo) Ti(IV) family of complexes of diamine bis(phenolato) ligands demonstrate markedly different cytotoxicity, supporting a chiral biological target of activity and participation of a ligand-bound active species.

Graphical abstract image for this article  (ID: b920786b)