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Green Chem., 2003, 5, 174 - 176, DOI: 10.1039/b211966h

Green heterocycle synthesis, isochromenones and artemidin

T. A. Bryson, J. J. Stewart, J. M. Gibson, P. S. Thomas and J. K. Berch

Organic transformations in near critical water, generated in heated stainless steel pressure reactors or microwave irradiated Teflon or glass pressure reactors, yield a green synthesis of isochromen-1-ones or isocourmarins. A synthesis of the isochromen-1-one artemidin using a combination of synthetic microwave and commercial microwave equipment is presented.

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