Issue 8, 2008
From the journal:

Journal of Analytical Atomic Spectrometry

Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera†

Shinji Motomura,a   Yousuke Kanayama,a   Hiromitsu Haba,b   Yasuyoshi Watanabeb  and  Shuichi Enomoto*ab  

* Corresponding authors

a Molecular Imaging Research Program, RIKEN Kobe Institute, Chuo-ku, Kobe, Hyogo, Japan
E-mail: motomura@riken.jp

b Metallomics Research Unit, RIKEN Wako Institute, Wako, Saitama, Japan
E-mail: semo@riken.jp

Abstract

We have demonstrated the feasibility of semiconductor Compton cameras for multiple molecular imaging in nuclear medicine. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enabled discrimination of the nuclides and accurate determination of the scattering angle for γ rays in wide energy range. Three radioactive tracers of 65ZnCl2, 85SrCl2, and iodinated (131I) methylnorcholestenol were injected to a living mouse and were measured simultaneously. Both two- and three-dimensional images of each tracer were obtained by a fixed-angle imaging with a single Compton camera, which reflected the different in vivo behavior of them.

Graphical abstract: Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B802964D
Article type
Paper
Submitted
20 Feb 2008
Accepted
11 Jun 2008
First published
08 Jul 2008

J. Anal. At. Spectrom., 2008,23, 1089-1092

Permissions

Request permissions

Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

S. Motomura, Y. Kanayama, H. Haba, Y. Watanabe and S. Enomoto, J. Anal. At. Spectrom., 2008, 23, 1089 DOI: 10.1039/B802964D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements