_tcm18-9556.gif )
High impact applications, properties and synthesis of exciting new materials
Also of interest
Physics, chemistry and biology of Soft Matter
Subscribers
Non-subscribers
- Purchase article PDF [£30 + taxes]
- Purchase article PDF member offer [£5 + taxes]
Free access
Paper
J. Mater. Chem., 2008, 18, 1204 - 1208, DOI: 10.1039/b718745a
Protein-passivated Fe3O4 nanoparticles: low toxicity and rapid heating for thermal therapy
Bappaditya Samanta, Haoheng Yan, Nicholas O. Fischer, Jing Shi, D. Joseph Jerry and Vincent M. Rotello
Thermotherapy is a promising technique for the minimally invasive elimination of solid tumors. Here we report the fabrication of protein-coated iron oxide NPs (12 nm core) for use as thermal therapeutic agents. These albumin-passivated NPs are stable under physiological conditions, with rapid heating and cell killing capacity upon alternating magnetic field (AMF) exposure. The mode of action is specific: no measurable cytotoxicity was observed for the particle without AMF or for AMF exposure without the particle.
RSS feed