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Communication

Lab Chip, 2007, 7, 1424 - 1427, DOI: 10.1039/b713324c

Integration of large-area polymer nanopillar arrays into microfluidic devices using in situ polymerization cast molding

Guofang Chen, Gregory T. McCandless, Robin L. McCarley and Steven A. Soper

Presented here is a simple and robust approach for the integration of mixed-scale (nm–cm) structures into fluidic devices. We report on devices composed of large-area polymer nanopillar arrays of high aspect ratio (33–667) integrated into microfluidic channels fabricated by cast-molding polymerization of methyl methacrylate with mechanically/lithographically patterned, nanoporous aluminium oxide (AAO) templates. The microchannels containing the nanopillar arrays can be chemically functionalized and used for a variety of applications, such as separation beds or solid-phase reactors/extractors.

Graphical abstract image for this article (ID: b713324c)